Structure of PDB 7ofv Chain A Binding Site BS01
Receptor Information
>7ofv Chain A (length=184) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SHMNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNV
MEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLY
YYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGP
LSKKGFYLAFQDVGACIALVSVRVFYKKAPLTVR
Ligand information
>7ofv Chain B (length=6) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
tWFRGg
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7ofv
NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands.
Resolution
1.43 Å
Binding residue
(original residue number in PDB)
E55 M60 D61 E62 Q71 L105 I159 M164 C191 I192 A193
Binding residue
(residue number reindexed from 1)
E30 M35 D36 E37 Q46 L80 I134 M139 C166 I167 A168
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:7ofv
,
PDBe:7ofv
,
PDBj:7ofv
PDBsum
7ofv
PubMed
34293864
UniProt
P54764
|EPHA4_HUMAN Ephrin type-A receptor 4 (Gene Name=EPHA4)
[
Back to BioLiP
]
