Structure of PDB 7o67 Chain A Binding Site BS01

Receptor Information
>7o67 Chain A (length=173) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSR
YFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECA
LLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVH
NLVKMGAPDAGLAEYLFDTHTLG
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain7o67 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7o67 Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin.
Resolution1.86 Å
Binding residue
(original residue number in PDB)		E62 E107 V110
Binding residue
(residue number reindexed from 1)		E59 E104 V107
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7o67, PDBe:7o67, PDBj:7o67
PDBsum7o67
PubMed34343376
UniProtQ8N4E7|FTMT_HUMAN Ferritin, mitochondrial (Gene Name=FTMT)

[Back to BioLiP]