Structure of PDB 7o0h Chain A Binding Site BS01

Receptor Information
>7o0h Chain A (length=566) Species: 2170205 (White-tufted-ear marmoset simian foamy virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLLQLPVEVKKTELNGFWDTGAQITCIPEAFLKEEIPIGEAQIKTLHTKL
QSVYYLKFKVLGRKVEAEVTTSPFDYVIISPSDIPWYKPQPLELTVKLPV
QDFKKELINKANINNEEKKQLAKLLDKYDVLWQQWENQVGHRKIPPHNIA
TGTVAPRPQRQYHINTKAKPSIQQVIDDLLKQGVLIKQTSVMNTPIYPVP
KPDGKWRMVLDYRAVNKTVPLIGAQNQHSLGILTNLVRQKYKSTIDLSNG
FWAHPITKDSQWITAFTWEGKQHVWTRLPQGFLNSPALFTADVVDLLKNI
PGISVYVDDIYFSTETVSEHLKILEKVFKILLEAGYIVSLKKSALLRYEV
TFLGFSITQTGRGLTSEFKDKIQNITSPRTLKELQSILGLFNFARNFVPN
FSEIIKPLYSLISTAEGNNIKWTSEHTRYLEEIVSALNHAGNLEQRDNES
PLVVKLNASPKTGYIRYYNKGGQKPIAYASHVFTNTELKFTPLEKLLVTM
HKALIKAIDLALGQPIEVYSPIISMQKLQKTPLPERKALSTRWITWLSYL
EDPRITFYYDKTLPDL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7o0h Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
Resolution3.09 Å
Binding residue
(original residue number in PDB)		Y167 Y202 D216 N221 Q232 H233 S234 G286 L288 N397 R400 K411 Y414 I417 S418
Binding residue
(residue number reindexed from 1)		Y162 Y197 D211 N216 Q227 H228 S229 G281 L283 N392 R395 K406 Y409 I412 S413
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7o0h, PDBe:7o0h, PDBj:7o0h
PDBsum7o0h
PubMed34232702
UniProtD5JWV1

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