Structure of PDB 7nri Chain A Binding Site BS01

Receptor Information
>7nri Chain A (length=785) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFE
DVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGE
SLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGV
SAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDL
ETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEV
SGNLAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQ
SMPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQME
GAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNT
GSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYAELSV
TNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYN
SLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFN
YGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDD
DHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAV
YFPHQASNYDPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTP
FISDKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIA
LQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nri The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase.
Resolution3.03 Å
Binding residue
(original residue number in PDB)		N422 G424 S425 F426 N427 F428 I430 L780
Binding residue
(residue number reindexed from 1)		N399 G401 S402 F403 N404 F405 I407 L757
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0043165 Gram-negative-bacterium-type cell outer membrane assembly
GO:0051205 protein insertion into membrane
GO:0071709 membrane assembly
Cellular Component
GO:0009279 cell outer membrane
GO:0016020 membrane
GO:0019867 outer membrane
GO:1990063 Bam protein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nri, PDBe:7nri, PDBj:7nri
PDBsum7nri
PubMed33854236
UniProtP0A940|BAMA_ECOLI Outer membrane protein assembly factor BamA (Gene Name=bamA)

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