Structure of PDB 7nrf Chain A Binding Site BS01

Receptor Information
>7nrf Chain A (length=368) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYAELSV
TNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYN
SLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFN
YGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDD
DHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAV
YFPHQDLSKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDMG
TVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFK
KYDGDKAEQFQFNIGKTW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7nrf The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		G424 S425 F426 N427 F428 I430 Q446 L780 K808
Binding residue
(residue number reindexed from 1)		G1 S2 F3 N4 F5 I7 Q23 L338 K366
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0071709 membrane assembly
Cellular Component
GO:0019867 outer membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:7nrf, PDBe:7nrf, PDBj:7nrf
PDBsum7nrf
PubMed33854236
UniProtP0A940|BAMA_ECOLI Outer membrane protein assembly factor BamA (Gene Name=bamA)

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