Structure of PDB 7nes Chain A Binding Site BS01

Receptor Information
>7nes Chain A (length=58) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTTFVALYDYESWIETDLSFKKGERLQIVNNTEGDWWLAHSLTTGQTGYI
PSNYVAPS
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain7nes Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7nes The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		T85 R107 S140
Binding residue
(residue number reindexed from 1)		T3 R25 S58
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Gene Ontology
Biological Process
GO:0006897 endocytosis
GO:0051666 actin cortical patch localization

View graph for
Biological Process
External links
PDB RCSB:7nes, PDBe:7nes, PDBj:7nes
PDBsum7nes
PubMed34076598
UniProtP00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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