Structure of PDB 7n3z Chain A Binding Site BS01

Receptor Information

>7n3z Chain A (length=379) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQELK
TEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKNHPLYHALQV
VKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALELD
SEGRCVMVELACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNLD
KIGKKIVLMGDVNVCRDLIDSADTLEQFSIPITDPMGGTKLEAQYRDKAI
QFIINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYTV
WNMLKNLRPSNYGSRIDFILVSLKLERCIKAADILPDILGSDHCPVYSDL
DILDDRIEPGTTQVPIPKFEARYKYNLRN

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7n3z Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7n3z Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
Resolution	1.99 Å
Binding residue (original residue number in PDB)	N25 E59
Binding residue (residue number reindexed from 1)	N14 E48
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.1.11.2: exodeoxyribonuclease III.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003824	catalytic activity
GO:0004518	nuclease activity
GO:0004519	endonuclease activity

	Biological Process
GO:0006281	DNA repair

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Molecular Function

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Biological Process

External links

PDB	RCSB:7n3z, PDBe:7n3z, PDBj:7n3z
PDBsum	7n3z
PubMed	36198268
UniProt	P38207\|APN2_YEAST DNA-(apurinic or apyrimidinic site) endonuclease 2 (Gene Name=APN2)

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