Structure of PDB 7mmw Chain A Binding Site BS01

Receptor Information

>7mmw Chain A (length=319) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SNILEMTKNYYDRSVSPVEYAYFDQSQNMRAINWNKIVDEKDLEVWNRVT
QNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVA
QIKNSLTEQEQVIYANFAFMVGVHARSYGTIFSTLCTSEQIEEAHEWVVD
NEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGK
LPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLD
KMIGLEKTYLHQLYDGFGLADEAIRFSLYNAGKFLQNLGYESPFTKEETR
IAPEVFAQLSARADENHDF

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

7mmw Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7mmw Ribonucleotide Reductase
Resolution	1.55 Å
Binding residue (original residue number in PDB)	G263 D266 E267
Binding residue (residue number reindexed from 1)	G268 D271 E272
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.17.4.1: ribonucleoside-diphosphate reductase.

Gene Ontology

	Molecular Function
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Biological Process
GO:0009263	deoxyribonucleotide biosynthetic process

	Cellular Component
GO:0005971	ribonucleoside-diphosphate reductase complex
GO:0016020	membrane

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External links

PDB	RCSB:7mmw, PDBe:7mmw, PDBj:7mmw
PDBsum	7mmw
PubMed
UniProt	F2I8X9

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