Structure of PDB 7mk3 Chain A Binding Site BS01

Receptor Information
>7mk3 Chain A (length=361) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGPDVSALQLLSNSFESVFDSPDDFYSDAKLVLSDGREVSFHRCVLSARS
SFFKSALAAAKKEKDAVKLELKEIAKDYEVGFDSVVTVLAYVYSSRVRPP
PKGVSECADENCCHVACRPAVDFMLEVLYLAFIFKIPELITLYQRHLLDV
VDKVVIEDTLVILKLANICGKACMKLLDRCKEIIVKSNVDMVSLEKSLPE
ELVKEIIDRRKELGLEVPKVKKHVSNVHKALDSDDIELVKLLLKEDHTNL
DDACALHFAVAYCNVKTATDLLKLDLADVNHRNPRGYTVLHVAAMRKEPQ
LILSLLEKGASASEATLEGRTALMIAKQATMAVECNNIPEQCKHSLKGRL
CVEILEQEDKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7mk3 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7mk3 Structural basis of NPR1 in activating plant immunity.
Resolution3.06 Å
Binding residue
(original residue number in PDB)		C150 C155 H157 C160
Binding residue
(residue number reindexed from 1)		C107 C112 H114 C117
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0009862 systemic acquired resistance, salicylic acid mediated signaling pathway
GO:2000022 regulation of jasmonic acid mediated signaling pathway
GO:2000031 regulation of salicylic acid mediated signaling pathway

View graph for
Biological Process
External links
PDB RCSB:7mk3, PDBe:7mk3, PDBj:7mk3
PDBsum7mk3
PubMed35545668
UniProtP93002|NPR1_ARATH Regulatory protein NPR1 (Gene Name=NPR1)

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