Structure of PDB 7mgt Chain A Binding Site BS01

Receptor Information

>7mgt Chain A (length=319) Species: 160 (Treponema pallidum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ARVREYSRAELVIGTLCRVRVYSKRPAAEVHAALEEVFTLLQQQEMVLSA
NRDDSALAALNAQAGSAPVVVDRSLYALLERALFFAEKSGGTFNPALGAV
VKLWNVPDPDALKEALTRCDFRQVHLRAGVSVGAPHTVQLAQAGMQLDLG
AIAKGFLADKIVQLLTAHALDSALVDLGGNIFALGLKYGAQRLEWNVGIR
DPHGPALVVSVRDCSVVTSGAYERFFERDGVRYHHIIDPVTGFPAHTDVD
SVSIFAPRSTDADALATACFVLGYEKSCALLREFPGVDALFIFPDKRVRA
SAGIVDRVRVLDARFVLER

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7mgt Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7mgt Inhibition of bacterial FMN transferase: A potential avenue for countering antimicrobial resistance.
Resolution	1.54 Å
Binding residue (original residue number in PDB)	A162 D284 T288
Binding residue (residue number reindexed from 1)	A151 D263 T267
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.7.1.180: FAD:protein FMN transferase.

Gene Ontology

	Molecular Function
GO:0016740	transferase activity
GO:0046872	metal ion binding

	Biological Process
GO:0017013	protein flavinylation

	Cellular Component
GO:0005886	plasma membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7mgt, PDBe:7mgt, PDBj:7mgt
PDBsum	7mgt
PubMed	34796555
UniProt	O83774\|APBE_TREPA FAD:protein FMN transferase (Gene Name=apbE)

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