Structure of PDB 7lzh Chain A Binding Site BS01

Receptor Information
>7lzh Chain A (length=798) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRPSSVNVGALFTYDSFIGRAAKPAVKAAMDDVNADQSVLKGIKLNIIFQ
DSNCSGFIGTMGALQLMENKVVAAIGPQSSGIAHMISYVANELHVPLLSF
GATDPTLSSLQFPYFLRTTQNDYFQMHAIADFLSYSGWRQVIAIFVDDEC
GRNGISVLGDVLAKKRSRISYKAAITPGADSSSIRDLLVSVNLMESRVFV
VHVNPDSGLNVFSVAKSLGMMASGYVWIATDWLPTAMDSMEHVDSDTMDL
LQGVVAFRHYTIESSVKRQFMARWKNLRPNDGFNSYAMYAYDSVWLVARA
LDVFFRENNNITFSNDIQLSALSVFNEGEKFMKIILGMNHTGVTGPIQFD
SDRNRVNPAYEVLNLEGTAPRTVGYWSNHSGLSVVHPETLYSRPPNTSTA
NQRLKGIIYPGEVTKPPRGWVFPNNGKPLRIGVPNRVSYTDYVSKDKNPP
GVRGYCIDVFEAAIELLPYPVPRTYILYGDGKRNPSYDNLVNEVVADNFD
VAVGDITIVTNRTRYVDFTQPFIESGLVVVAPVKEAKSSPWSFLKPFTIE
MWAVTGGFFLFVGAMVWILEQLITIFWFSFSTMSLGRFVLIIWLFVVLII
NSSYTASLTSILTIRQLTSRIEGIDSLVTSNEPIGVQDGTFARNYLINEL
NILPSRIVPLKDEEQYLSALQRGPNAGGVAAIVDELPYIEVLLTNSNCKF
RTVGQEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHRKWLNYK
HECSMQISNSEDSQLSLKSFWGLFLICGITCFMALTVFFWRVFWQYQR
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain7lzh Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lzh Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Resolution3.57 Å
Binding residue
(original residue number in PDB)		R501 N549 Y552 D570 T572 Q725 G727 T728 F729 E773 Y776
Binding residue
(residue number reindexed from 1)		R436 N484 Y487 D505 T507 Q637 G639 T640 F641 E685 Y688
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7lzh, PDBe:7lzh, PDBj:7lzh
PDBsum7lzh
PubMed34161757
UniProtQ8GXJ4|GLR34_ARATH Glutamate receptor 3.4 (Gene Name=GLR3.4)

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