Structure of PDB 7lza Chain A Binding Site BS01

Receptor Information

>7lza Chain A (length=219) Species: 100226 (Streptomyces coelicolor A3(2))

GMRVLIVEDEPYLAEAIRDGLRLEAIAADIAGDGDTALELLSVNAYDIAV
LDRDIPGPSGDEIAERIVASGSGMPILMLTAADRLDDKASGFGLGADDYL
TKPFELQELALRLRALDRRRASRPPVREIAGLRLDPFRREVYRGGRYVAL
TRKQFAVLEVLVAAEGGVVSAEELLERAWDENADPFTNAVRITVSALRKR
LGEPGIIATVPGVGYRIDT

Ligand information

• Ligand ID: BEF
• InChI: InChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
• InChIKey: OGIAHMCCNXDTIE-UHFFFAOYSA-K
• SMILES:
  OpenEye OEToolkits 1.5.0: [Be-](F)(F)F
  ACDLabs 10.04
  CACTVS 3.341: F[Be-](F)F
• Formula: Be F3
• Name: BERYLLIUM TRIFLUORIDE ION
• PDB chain: 7lza Chain A Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7lza Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
• Resolution: 2.03 Å
• Binding residue (original residue number in PDB): D51 R52 D53 T79 A80 K101
• Binding residue (residue number reindexed from 1): D52 R53 D54 T80 A81 K102
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0000156 phosphorelay response regulator activity
• GO:0000976 transcription cis-regulatory region binding
• GO:0003677 DNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0000160 phosphorelay signal transduction system
• GO:0006355 regulation of DNA-templated transcription

Cellular Component

• GO:0005829 cytosol
• GO:0032993 protein-DNA complex

External links

• PDB: RCSB:7lza, PDBe:7lza, PDBj:7lza
• PDBsum: 7lza
• PubMed: 34342276
• UniProt: Q8CJW1