Structure of PDB 7lz9 Chain A Binding Site BS01

Receptor Information

>7lz9 Chain A (length=208) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GMRVLIVEDEPYLAEAIRDGLRLEAIAADIAGDGDTALELLSVNAYDIAV
LDRDIPGPSGDEIAERIVASGSGMPILMLTAAGADDYLTKPFELQELALR
LRALDRRRAHSRPPVREIAGLRLDPFRREVYRGGRYVALTRKQFAVLEVL
VAAEGGVVSAEELLERAWDENADPFTNAVRITVSALRKRLGEPGIIATVP
GVGYRIDT

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7lz9 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7lz9 Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
Resolution	2.3 Å
Binding residue (original residue number in PDB)	D8 D51 D53
Binding residue (residue number reindexed from 1)	D9 D52 D54
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000156	phosphorelay response regulator activity
GO:0000976	transcription cis-regulatory region binding
GO:0003677	DNA binding
GO:0046872	metal ion binding

	Biological Process
GO:0000160	phosphorelay signal transduction system
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005829	cytosol
GO:0032993	protein-DNA complex

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Cellular Component

External links

PDB	RCSB:7lz9, PDBe:7lz9, PDBj:7lz9
PDBsum	7lz9
PubMed	34342276
UniProt	Q8CJW1

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