Structure of PDB 7lz2 Chain A Binding Site BS01

Receptor Information
>7lz2 Chain A (length=252) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSAMGSKPLRIGVPNRVSYTDYVSKDKNPPGVRGYCIDVFEAAIELLPYP
VPRTYILYGDGKRNPSYDNLVNEVVADNFDVAVGDITIVTNRTRYVDFTQ
PFIESGLVVVAPVKEAGTIEGIDSLVTSNEPIGVQDGTFARNYLINELNI
LPSRIVPLKDEEQYLSALQRGPNAGGVAAIVDELPYIEVLLTNSNCKFRT
VGQEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHRKWLNYKHE
CS
Ligand information
Ligand IDMET
InChIInChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKeyFFEARJCKVFRZRR-BYPYZUCNSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[CH](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCCC(C(=O)O)N
CACTVS 3.341CSCC[C@H](N)C(O)=O
OpenEye OEToolkits 1.5.0CSCC[C@@H](C(=O)O)N
ACDLabs 10.04O=C(O)C(N)CCSC
FormulaC5 H11 N O2 S
NameMETHIONINE
ChEMBLCHEMBL42336
DrugBankDB00134
ZINCZINC000001532529
PDB chain7lz2 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7lz2 Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Resolution1.5 Å
Binding residue
(original residue number in PDB)
R16 Y67 T87 R92 Q135 D136 T138 F139 E183 Y186
Binding residue
(residue number reindexed from 1)
R16 Y67 T87 R92 Q135 D136 T138 F139 E183 Y186
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:7lz2, PDBe:7lz2, PDBj:7lz2
PDBsum7lz2
PubMed34161757
UniProtQ8GXJ4|GLR34_ARATH Glutamate receptor 3.4 (Gene Name=GLR3.4)

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