Structure of PDB 7lx9 Chain A Binding Site BS01

Receptor Information
>7lx9 Chain A (length=160) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI
GRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCAAI
NMVFQMGETGGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITT
FRTGTWDAYK
Ligand information
Ligand IDYGM
InChIInChI=1S/C10H12/c1-2-3-7-10-8-5-4-6-9-10/h2,4-6,8-9H,1,3,7H2
InChIKeyPBGVMIDTGGTBFS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01
CACTVS 3.385
OpenEye OEToolkits 2.0.7		C=CCCc1ccccc1
FormulaC10 H12
Name(but-3-en-1-yl)benzene
ChEMBL
DrugBank
ZINCZINC000001692476
PDB chain7lx9 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7lx9 Energy penalties enhance flexible receptor docking in a model cavity.
Resolution1.19 Å
Binding residue
(original residue number in PDB)		V87 Y88 A99 M102 L118 F153
Binding residue
(residue number reindexed from 1)		V87 Y88 A99 M102 L116 F151
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E11 D20
Catalytic site (residue number reindexed from 1) E11 D20
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0030430 host cell cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:7lx9, PDBe:7lx9, PDBj:7lx9
PDBsum7lx9
PubMed34475217
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E)

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