Structure of PDB 7lmk Chain A Binding Site BS01

Receptor Information
>7lmk Chain A (length=158) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKNRISWVGDAVKTDGKKSYYKKVCIDSETLEVGDCVSVIPDDSSKPLYL
ARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQLS
YIHSKVQVIYKAPSGAGSATYFYQLWYDQDYARFESPPKTQPTEDNKYKF
CASCARLA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lmk DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Resolution2.647 Å
Binding residue
(original residue number in PDB)		I763 D765 Y772 W793 E818 Y824
Binding residue
(residue number reindexed from 1)		I40 D42 Y49 W70 E95 Y101
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003682 chromatin binding

View graph for
Molecular Function
External links
PDB RCSB:7lmk, PDBe:7lmk, PDBj:7lmk
PDBsum7lmk
PubMed33941775
UniProtQ24K09|DNMT1_BOVIN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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