Structure of PDB 7lm3 Chain A Binding Site BS01

Receptor Information
>7lm3 Chain A (length=185) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIHAYTEGGKPLRTIYLPKLLKKVFLDVVKPNTKKNLETCGILCGKLRQN
AFFITHLVIPLQEATSDACGTTDEASLFEFQDKHNLLTLGWIHTHPTQTC
FMSSVDLHTHCSYQLMLPEAIAIVMAPSKNTSGIFRLLDPEGLQTIVKCR
KPGLFHPHEGKVYTMVAQPGHVREINSKLQVVDLR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7lm3 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7lm3 Crystal structure of the Thr316Ala mutant of a yeast JAMM deubiquitinase: implication of active-site loop dynamics in catalysis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H356 C397 H404 H406
Binding residue
(residue number reindexed from 1)		H108 C149 H156 H158
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.19.-
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0061578 K63-linked deubiquitinase activity
GO:0140492 metal-dependent deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination
GO:0070536 protein K63-linked deubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:7lm3, PDBe:7lm3, PDBj:7lm3
PDBsum7lm3
PubMed34100774
UniProtQ9P371|SST2_SCHPO AMSH-like protease sst2 (Gene Name=sst2)

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