Structure of PDB 7lgd Chain A Binding Site BS01

Receptor Information
>7lgd Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
REAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>7lgd Chain F (length=9) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SPRWYFYYL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lgd CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Resolution2.88 Å
Binding residue
(original residue number in PDB)
Y7 R62 N63 I66 Y67 A69 Q70 T73 E76 S77 N80 Y84 Y99 D114 Y116 Y123 T143 K146 W147 E152 Q155 R156 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 R62 N63 I66 Y67 A69 Q70 T73 E76 S77 N80 Y84 Y99 D114 Y116 Y123 T143 K146 W147 E152 Q155 R156 Y159 E163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7lgd, PDBe:7lgd, PDBj:7lgd
PDBsum7lgd
PubMed33945786
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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