Structure of PDB 7l67 Chain A Binding Site BS01

Receptor Information
>7l67 Chain A (length=135) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ACPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKE
EQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEP
NNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQI
Ligand information
Ligand IDFUC
InChIInChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6+/m0/s1
InChIKeySHZGCJCMOBCMKK-SXUWKVJYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)C
OpenEye OEToolkits 1.5.0CC1C(C(C(C(O1)O)O)O)O
OpenEye OEToolkits 1.5.0C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O)O)O)O
CACTVS 3.341C[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
FormulaC6 H12 O5
Namealpha-L-fucopyranose;
alpha-L-fucose;
6-deoxy-alpha-L-galactopyranose;
L-fucose;
fucose
ChEMBLCHEMBL1232862
DrugBankDB04473
ZINCZINC000001532814
PDB chain7l67 Chain B Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l67 Structural analysis of carbohydrate binding by the macrophage mannose receptor CD206.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		E725 N727 E733 N747 I749
Binding residue
(residue number reindexed from 1)		E99 N101 E107 N121 I123
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7l67, PDBe:7l67, PDBj:7l67
PDBsum7l67
PubMed33545173
UniProtP22897|MRC1_HUMAN Macrophage mannose receptor 1 (Gene Name=MRC1)

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