Structure of PDB 7l4m Chain A Binding Site BS01

Receptor Information
>7l4m Chain A (length=350) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIRLPNPMIGFGVPNEPGLITHRSLPELARGPPFFYYENVALTPKGVWET
ISRHLFEIPPEFVDSKYFCVAARKRGYIHNLPINNRFQIQPPPKYTIHDA
FPLSKRWWPEWDKRTKLNCILTCTGSAQLTNRIRVALEPYNEEPEPPKHV
QRYVIDQCKKWNLVWVGKNKAAPLEPDEMESILGFPKNHTRGGGMSRTER
FKSLGNSFQVDTVAYHLSVLKPIFPHGINVLSLFTGIGGGEVALHRLQIK
MKLVVSVEISKVNRNILKDFWEQTNQTGELIEFSDIQHLTNDTIEGLMEK
YGGFDLVIGGSPCNNLAGGNRVSRVGLEGDQSSLFFEYCRILEVVRARMR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l4m Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Resolution2.805 Å
Binding residue
(original residue number in PDB)
S400 R406 S470 R471 T472 G592 R595
Binding residue
(residue number reindexed from 1)
S126 R132 S196 R197 T198 G318 R321
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7l4m, PDBe:7l4m, PDBj:7l4m
PDBsum7l4m
PubMed34078593
UniProtQ9M548|DRM2_ARATH DNA (cytosine-5)-methyltransferase DRM2 (Gene Name=DRM2)

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