Structure of PDB 7l4c Chain A Binding Site BS01

Receptor Information
>7l4c Chain A (length=353) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPIRLPNPMIGFGVPNEPGLITHRSLPELARGPPFFYYENVALTPKGVWE
TISRHLFEIPPEFVDSKYFCVAARKRGYIHNLPINNRFQIQPPPKYTIHD
AFPLSKRWWPEWDKRTKLNCILTCTGSAQLTNRIRVALEPYNEEPEPPKH
VQRYVIDQCKKWNLVWVGKNKAAPLEPDEMESILGFPKNHTRGGGMSRTE
RFKSLGNSFQVDTVAYHLSVLKPIFPHGINVLSLFTGIGGGEVALHRLQI
KMKLVVSVEISKVNRNILKDFWEQTNQTGELIEFSDIQHLTNDTIEGLME
KYGGFDLVIGGSPCNNLAGGNRVSRVGLEGDQSSLFFEYCRILEVVRARM
RGS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l4c Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Resolution2.11 Å
Binding residue
(original residue number in PDB)		L278 P318 K319 S400 A401 Q402 R406 S470 R471 T472 G592 N594 R595 R598
Binding residue
(residue number reindexed from 1)		L5 P45 K46 S127 A128 Q129 R133 S197 R198 T199 G319 N321 R322 R325
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7l4c, PDBe:7l4c, PDBj:7l4c
PDBsum7l4c
PubMed34078593
UniProtQ9M548|DRM2_ARATH DNA (cytosine-5)-methyltransferase DRM2 (Gene Name=DRM2)

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