Structure of PDB 7l48 Chain A Binding Site BS01

Receptor Information
>7l48 Chain A (length=522) Species: 32644 (unidentified) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTITKTLKLRIVRPYNSAEVEKIVADEKNNREKIALEKNKDKVKEACSKH
LKVAAYCTTQVERNACLFCKARKLDDKFYQKLRGQFPDAVFWQEISEIFR
QLQKQAAEIYNQSLIELYYEIFIKGKGIANASSVEHYLSDVCYTRAAELF
KNAAIASGLRSKIKSNFRLKELKNMKSGLPTTKSDNFPIPLVKQKGGQYT
GFEISNHNSDFIIKIPFGRWQVKKEIDKYRPWEKFDFEQVQKSPKPISLL
LSTQRRKRNKGWSKDEGTEAEIKKVMNGDYQTSYIEVKRGSKICEKSAWM
LNLSIDVPKIDKGVDPSIIGGIDVGVKSPLVCAINNAFSRYSISDNDLFH
FNKKMFARRRILLKKNRHKRAGHGAKNKLKPITILTEKSERFRKKLIERW
ACEIADFFIKNKVGTVQMENLESMKRKEDSYFNIRLRGFWPYAEMQNKIE
FKLKQYGIEIRKVAPNNTSKTCSKCGHLNNYFNFEYRKKNKFPHFKCEKC
NFKENADYNAALNISNPKLKST
Ligand information
>7l48 Chain E (length=144) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcuucaccaaaagcugucccuuaggggauagaacuugagugaaggugg
gcugcuugcaucagccuaaugucgagaagugcuuucuucggaaaguaacc
cucgaaacaaauucauuuagacgaaugaaggaaugcaacaguug
...<<<<<<<<...<<<<<<<......>>>>>>..>.>>.>>>>>>...(
((((.<<<<<<))))).....<<<<<..<<<<<<<<....>>>>>>.>>.
>>>>>.....<<<<.<<..>>.>>>>......>>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7l48 Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR-Cas12f nuclease.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
T7 K8 T9 R13 V15 R16 K31 R66 N67 C72 K73 K76 D79 Y82 F94 W95 S99 R171 P183 P191 D213 S255 T256 Q257 R258 R259 R261 K263 T271 E272 E298 K299 R361 N369 K372 R373 A374 G375 H376 G377 A378 K379 N380 K381 R394 F395 K398 E401 C405 K451 F454 K492
Binding residue
(residue number reindexed from 1)
T4 K5 T6 R10 V12 R13 K28 R63 N64 C69 K70 K73 D76 Y79 F91 W92 S96 R168 P180 P188 D210 S252 T253 Q254 R255 R256 R258 K260 T268 E269 E295 K296 R358 N366 K369 R370 A371 G372 H373 G374 A375 K376 N377 K378 R391 F392 K395 E398 C402 K448 F451 K489
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