Structure of PDB 7l3c Chain A Binding Site BS01

Receptor Information
>7l3c Chain A (length=162) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI
GRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCAAI
NMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVI
TTFRTGTWDAYK
Ligand information
Ligand IDOXE
InChIInChI=1S/C8H10/c1-7-5-3-4-6-8(7)2/h3-6H,1-2H3
InChIKeyCTQNGGLPUBDAKN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		Cc1ccccc1C
ACDLabs 10.04c1cccc(c1C)C
FormulaC8 H10
NameORTHO-XYLENE
ChEMBLCHEMBL45005
DrugBank
ZINCZINC000000968282
PDB chain7l3c Chain A Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7l3c Temperature artifacts in protein structures bias ligand-binding predictions.
Resolution1.31 Å
Binding residue
(original residue number in PDB)		A99 L118
Binding residue
(residue number reindexed from 1)		A99 L118
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l3c, PDBe:7l3c, PDBj:7l3c
PDBsum7l3c
PubMed34667539
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E)

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