Structure of PDB 7l0a Chain A Binding Site BS01

Receptor Information
>7l0a Chain A (length=249) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLVPRGSHMAYISLNYHSPTIGMHQNLTVILPEDQSFFNSDTTVKPLKTL
MLLHGLSSDETTYMRYTSIERYANEHKLAVIMPNVDHSAYANMAYGHSYY
DYILEVYDYVHQIFPLSKKRDDNFIAGHSMGGYGTIKFALTQGDKFAKAV
PLSAVFEAQNLMDLEWNDFSKEAEHDPYYLLDKAVAEDKQIPKLLIMCGK
QDFLYQDNLDFIDYLSRINVPYQFEDGPGDHDYAYWDQAIKRAITWMVN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7l0a Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7l0a Structure-guided microbial targeting of antistaphylococcal prodrugs.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		L47 S120 M121
Binding residue
(residue number reindexed from 1)		L56 S129 M130
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.2.12: S-formylglutathione hydrolase.
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0018738 S-formylglutathione hydrolase activity
Biological Process
GO:0046294 formaldehyde catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7l0a, PDBe:7l0a, PDBj:7l0a
PDBsum7l0a
PubMed34279224
UniProtQ2FUY3

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