Structure of PDB 7kzh Chain A Binding Site BS01

Receptor Information
>7kzh Chain A (length=182) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEKG
YCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPANSVFTTKWI
WYWKNESGTWIQYGENSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQ
GMIQTNIASKTQKDVIRRPTFVPQWYVQQMKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7kzh Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7kzh Poly(ADP-ribose) potentiates ZAP antiviral activity.
Resolution2.49 Å
Binding residue
(original residue number in PDB)		C513 C521 C527 H531
Binding residue
(residue number reindexed from 1)		C5 C13 C19 H23
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7kzh, PDBe:7kzh, PDBj:7kzh
PDBsum7kzh
PubMed35130321
UniProtQ7Z2W4|ZCCHV_HUMAN Zinc finger CCCH-type antiviral protein 1 (Gene Name=ZC3HAV1)

[Back to BioLiP]