Structure of PDB 7kz1 Chain A Binding Site BS01
Receptor Information
>7kz1 Chain A (length=143) Species:
9606
(Homo sapiens) [
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KKWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKY
PSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELH
GIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLS
Ligand information
>7kz1 Chain C (length=12) [
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ccagcgugcagc
Receptor-Ligand Complex Structure
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PDB
7kz1
Structural Insights into the Mechanism of Base Excision by MBD4.
Resolution
1.62 Å
Binding residue
(original residue number in PDB)
L466 N467 R468 H535 G536 G538 Y540 D560 K562
Binding residue
(residue number reindexed from 1)
L31 N32 R33 H100 G101 G103 Y105 D125 K127
Enzymatic activity
Enzyme Commision number
3.2.2.-
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003824
catalytic activity
Biological Process
GO:0006281
DNA repair
GO:0006284
base-excision repair
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Molecular Function
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Biological Process
External links
PDB
RCSB:7kz1
,
PDBe:7kz1
,
PDBj:7kz1
PDBsum
7kz1
PubMed
34107280
UniProt
O95243
|MBD4_HUMAN Methyl-CpG-binding domain protein 4 (Gene Name=MBD4)
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