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Receptor Information

>7kx9 Chain A (length=734) Species: 31330 (Ephydatia fluviatilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SQRGSSGQPVPVSANYLPLKGNMDGVFKYAVGFNPPVEDIRSRSQLLNEH
KELIGLTRVFDGSTLYVPKRICEQRLDLMSTRQTDGASIKVTISLVDSVK
NRDVVQLMNVIFKRILRSLKLQRIGRDYYDANSPLEVPQHKMQLWPGYVT
AINRHEGGLMLVLDVSHRVMKTDTALDFLYELYHFKQLVGSVVLTRYNNR
TYEIDDIAWDKNPRCAFQDHAGSQITFVDYYKRAYDLDITDLEQPLLIHR
PKEMVCLVPELCAMTGLTDAARSDFKVMKDLAVHTRVPPEKRAESFRKFI
QRLNTTKEASELLHSWGLVLDSRMLDMQGRRLPPEKILFKHSSIVANMEA
DWSRECLKEHVISAVSLLDWAVLFVRKDQGKATDFVNMLSKVCPPIGMEV
HEPKMVEVVNDRTESYLRALRELIAPRLQMVVIVFPTSRDDRYSAVKKLC
CIESPIPSQVLIARTITQQQKLRSVAQKVALQMNAKLGGELWAVEIPLKS
CMVVGIDVYHDKSYGNKSIAGFVASTNPSFTRWYSRTAMQEQSQELIHEL
KLCMQAALKKYNEMNQSLPERIIVFRDGVGEGREEYVSEFEVPQFNSCFS
IFGENYCPKLAVVVVQKRITTRIFGRSGHSYDNPPPGVIVDHTITKSYDF
YLVSQHVRQGTVSPTYYRVIYDKSGLKPDHLQRLTYKLTHMYYNWPGTIR
TPAPCNYAHKLAFLVGKSLHRDPAHELSDRLFFL

>7kx9 Chain B (length=24) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ucucuugaguuggacaaauggcag

........................

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7kx9 Structural basis for piRNA targeting.
Resolution	3.5 Å
Binding residue (original residue number in PDB)	Y435 Y440 F455 H458 F465 Y468 Y473 T538 R539 S691 Y696 K700 Q712 V713 I715 T718 Q735 T914 Y945 R953 L987
Binding residue (residue number reindexed from 1)	Y197 Y202 F217 H220 F227 Y230 Y235 T285 R286 S438 Y443 K447 Q459 V460 I462 T465 Q482 T661 Y692 R700 L734

Enzyme Commision number

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

PDB	RCSB:7kx9, PDBe:7kx9, PDBj:7kx9
PDBsum	7kx9
PubMed	34471284
UniProt	D5MRY8

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Structure of PDB 7kx9 Chain A Binding Site BS01