Structure of PDB 7kx7 Chain A Binding Site BS01

Receptor Information
>7kx7 Chain A (length=729) Species: 31330 (Ephydatia fluviatilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQRGSSGQPVPVSANYLPLKGNMDGVFKYAVGFNPPVEDIRSRSQLLNEH
KELIGLTRVFDGSTLYVPKRICEQRLDLMSTRQTDGASIKVTISLVDSVK
NRDVVQLMNVIFKRILRSLKLQRIGRDYYDANSPLEVPQHKMQLWPGYVT
AINRHEGGLMLVLDVSHRVMKTDTALDFLYELYHFKQLVGSVVLTRYNNR
TYEIDDIAWDKNPRCAFQDHAGSQITFVDYYKRAYDLDITDLEQPLLIHR
PKMVCLVPELCAMTGLTDAARSDFKVMKDLAVHTRVPPEKRAESFRKFIQ
RLNTTKEASELLHSWGLVLDSRMLDMQGRRLPPEKILFKHSSIVANMEAD
WSRECLKEHVISAVSLLDWAVLFVRKDQGKATDFVNMLSKVCPPIGMEVH
EPKMVEVVNDRTESYLRALRELIAPRLQMVVIVFPTSRDDRYSAVKKLCC
IESPIPSQVLIARTITQQQKLRSVAQKVALQMNAKLGGELWAVEIPLKSC
MVVGIDVYHDKSYGNKSIAGFVASTNPSFTRWYSRTAMQELIHELKLCMQ
AALKKYNEMNQSLPERIIVFRDGVGEGREEYVSEFEVPQFNSCFSIFGEN
YCPKLAVVVVQKRITTRIFGRSGHSYDNPPPGVIVDHTITKSYDFYLVSQ
HVRQGTVSPTYYRVIYDKSGLKPDHLQRLTYKLTHMYYNWPGTIRTPAPC
NYAHKLAFLVGKSLHRDPAHELSDRLFFL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7kx7 Structural basis for piRNA targeting.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		Y435 R438 Y440 F455 D457 Y468 Y469 Y473 V508 C509 D693 Y696 Q712 V713 L714 I715 T718 Q735 K963 L987
Binding residue
(residue number reindexed from 1)		Y197 R200 Y202 F217 D219 Y230 Y231 Y235 V254 C255 D439 Y442 Q458 V459 L460 I461 T464 Q481 K705 L729
Enzymatic activity
Enzyme Commision number 3.1.26.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7kx7, PDBe:7kx7, PDBj:7kx7
PDBsum7kx7
PubMed34471284
UniProtD5MRY8

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