Structure of PDB 7knf Chain A Binding Site BS01

Receptor Information
>7knf Chain A (length=506) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VANKVCLIVIDGWGVSEDPYGNAILNAQTPVMDKLCSGNWAQIEAHGLHV
GLPEGLMGNSEVGHLNIGAGRVIYQDIVRINLAVKNNKFVTNESLVDACD
RAKNGNGRLHLAGLVSDGGVHSHIDHMFALVKAIKELGVPELYLHFYGDG
RDTSPNSGVGFLEQTLEFLEKTTGYGKLATVVGRYYAMDRDNRWERINVA
YEAMIGGVGETSDEAGVVEVVRKRYAADETDEFLKPIILQGEKGRVQNDD
TIIFFDYRADRMREISAAMGMSKLAHPSNLQVYGMTQYKAEFPFKSLFPP
ASNKNVLAEWLAEQKVSQFHCAETEKYAHVTFFFNGGLEKQFEGEERCLV
PSPKVATYDLQPEMSAAGVADKMIEQLEAGTHPFIMCNFAPPDMVGHTGV
YEAAVKACEATDIAIGRIYEATQKHGYSLMVTADHGNAEKMKAPDGGKHT
AHTCYRVPLTLSHPGFKFVDPADRHPALCDVAPTVLAIMGLPQPAEMTGV
SIVQKI
Ligand information
>7knf Chain C (length=13) Species: 6239 (Caenorhabditis elegans) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YDYPGDHCYLYGT
Receptor-Ligand Complex Structure
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PDB7knf Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		N85 E87 V88 Q101 D102 R284 R289 T319 P333 F366 H485
Binding residue
(residue number reindexed from 1)		N59 E61 V62 Q75 D76 R258 R263 T286 P300 F333 H452
Enzymatic activity
Enzyme Commision number 5.4.2.12: phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004619 phosphoglycerate mutase activity
GO:0016853 isomerase activity
GO:0030145 manganese ion binding
GO:0046537 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006007 glucose catabolic process
GO:0006096 glycolytic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7knf, PDBe:7knf, PDBj:7knf
PDBsum7knf
PubMed33812994
UniProtG5EFZ1|GPMI_CAEEL 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (Gene Name=ipgm-1)

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