Structure of PDB 7kfa Chain A Binding Site BS01
Receptor Information
>7kfa Chain A (length=92) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
TATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTK
ILHVFHGLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQ
Ligand information
>7kfa Chain D (length=12) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
FVPTTaaEAPCA
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7kfa
Identification of a PCSK9-LDLR disruptor peptide with in vivo function.
Resolution
2.45 Å
Binding residue
(original residue number in PDB)
W72 F150 A151 Q152
Binding residue
(residue number reindexed from 1)
W12 F90 A91 Q92
Enzymatic activity
Enzyme Commision number
3.4.21.-
External links
PDB
RCSB:7kfa
,
PDBe:7kfa
,
PDBj:7kfa
PDBsum
7kfa
PubMed
34547225
UniProt
Q8NBP7
|PCSK9_HUMAN Proprotein convertase subtilisin/kexin type 9 (Gene Name=PCSK9)
[
Back to BioLiP
]
