Structure of PDB 7kev Chain A Binding Site BS01
Receptor Information
>7kev Chain A (length=92) Species:
9606
(Homo sapiens) [
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TATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTK
ILHVFHGLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQ
Ligand information
>7kev Chain C (length=12) Species:
32630
(synthetic construct) [
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FVSTTaaDRPCG
Receptor-Ligand Complex Structure
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PDB
7kev
Identification of a PCSK9-LDLR disruptor peptide with in vivo function.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
W72 F150 A151 Q152
Binding residue
(residue number reindexed from 1)
W12 F90 A91 Q92
Enzymatic activity
Enzyme Commision number
3.4.21.-
External links
PDB
RCSB:7kev
,
PDBe:7kev
,
PDBj:7kev
PDBsum
7kev
PubMed
34547225
UniProt
Q8NBP7
|PCSK9_HUMAN Proprotein convertase subtilisin/kexin type 9 (Gene Name=PCSK9)
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