Structure of PDB 7kd5 Chain A Binding Site BS01

Receptor Information

>7kd5 Chain A (length=428) Species: 152219,1327989

IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVA
ATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNG
KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNL
QEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKN
KHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFK
GQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGA
VALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAA
SGRQTVDAALAAAQTNAAAKSSAASPAALSGYKMTLLALIKESIPNQAKR
QKFEMQVGGIRNEQDFKNLRREIIRSAA

Ligand information

• Ligand ID: GLC
• InChI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• InChIKey: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C(C1C(C(C(C(O1)O)O)O)O)O
  OpenEye OEToolkits 1.5.0: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
  CACTVS 3.341: OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
  CACTVS 3.341: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
  ACDLabs 10.04: OC1C(O)C(OC(O)C1O)CO
• Formula: C6 H12 O6
• Name: alpha-D-glucopyranose;
  alpha-D-glucose;
  D-glucose;
  glucose
• ChEMBL: CHEMBL423707
• ZINC: ZINC000003861213
• PDB chain: 7kd5 Chain B Residue 1

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7kd5 Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions.
• Resolution: 1.551 Å
• Binding residue (original residue number in PDB): D14 K15 E111 Y155 W230
• Binding residue (residue number reindexed from 1): D13 K14 E110 Y154 W229
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0015144 carbohydrate transmembrane transporter activity

Biological Process

• GO:0008643 carbohydrate transport
• GO:0055085 transmembrane transport

External links

• PDB: RCSB:7kd5, PDBe:7kd5, PDBj:7kd5
• PDBsum: 7kd5
• PubMed: 34578318
• UniProt: A0A4P1LXE0;
  Q91MK1