Structure of PDB 7kb7 Chain A Binding Site BS01

Receptor Information
>7kb7 Chain A (length=218) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NADSLPERIDLFVSLFDYNSATTSYDIRSIQTDFPTRLLTPDSMLPQTSE
YPLKDIQLLYKLAQSCTGKLPLSPLITEPLVFTRSLCKGSSLSPRWFARS
GLIHPGGGTYAFRYAEKYPAQFANLLPYMHIQERPNAAEGTLLYHLQNMG
EDAINALVSGASMFGSGSDLWLRKGDIYYLFNEETWLTNANKAGLSYSLL
SADCFIQRGNICWDVEDH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7kb7 Chain A Residue 310 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7kb7 Sensor Domain of Histidine Kinase VxrA of Vibrio cholerae - A Hairpin-swapped Dimer and its Conformational Change.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D238 D249
Binding residue
(residue number reindexed from 1)		D203 D214
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
External links
PDB RCSB:7kb7, PDBe:7kb7, PDBj:7kb7
PDBsum7kb7
PubMed33753465
UniProtQ9KM24|VXRA_VIBCH Sensor histidine kinase VxrA (Gene Name=vxrA)

[Back to BioLiP]