Structure of PDB 7k6q Chain A Binding Site BS01

Receptor Information
>7k6q Chain A (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFMTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>7k6q Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacggattctcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatccgat
Receptor-Ligand Complex Structure
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PDB7k6q Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
H39 R42 P43 T45 R72 R83 Q85 S86 R116 V117 T118
Binding residue
(residue number reindexed from 1)
H3 R6 P7 T9 R36 R47 Q49 S50 R80 V81 T82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7k6q, PDBe:7k6q, PDBj:7k6q
PDBsum7k6q
PubMed33479126
UniProtP84233|H32_XENLA Histone H3.2

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