Structure of PDB 7k2r Chain A Binding Site BS01

Receptor Information
>7k2r Chain A (length=284) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLY
AVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHI
YAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAV
GGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGY
DGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGH
TFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7k2r Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Y334 S363 R380 N382 R415 R483 S508 Y525 S555 A556 Y572 F577 S602
Binding residue
(residue number reindexed from 1)		Y9 S38 R55 N57 R90 R158 S183 Y200 S230 A231 Y247 F252 S277
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7k2r, PDBe:7k2r, PDBj:7k2r
PDBsum7k2r
PubMed33683866
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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