Structure of PDB 7k2p Chain A Binding Site BS01

Receptor Information
>7k2p Chain A (length=283) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYA
VGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIY
AVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVG
GFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYD
GQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHT
FLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7k2p Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.
Resolution2.11 Å
Binding residue
(original residue number in PDB)		Y334 S363 R380 N382 R415 R483 S508 G509 Y525 S555 A556 Y572 F577 S602
Binding residue
(residue number reindexed from 1)		Y8 S37 R54 N56 R89 R157 S182 G183 Y199 S229 A230 Y246 F251 S276
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7k2p, PDBe:7k2p, PDBj:7k2p
PDBsum7k2p
PubMed33683866
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

[Back to BioLiP]