Structure of PDB 7k2f Chain A Binding Site BS01

Receptor Information
>7k2f Chain A (length=285) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLL
YAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGH
IYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYA
VGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGG
YDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDG
HTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7k2f Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning.
Resolution2.37 Å
Binding residue
(original residue number in PDB)
Y334 S363 R380 N382 R415 R483 S508 G509 Y525 S555 Y572
Binding residue
(residue number reindexed from 1)
Y10 S39 R56 N58 R91 R159 S184 G185 Y201 S231 Y248
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7k2f, PDBe:7k2f, PDBj:7k2f
PDBsum7k2f
PubMed33683866
UniProtQ14145|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)

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