Structure of PDB 7jya Chain A Binding Site BS01

Receptor Information
>7jya Chain A (length=370) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARY
GHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQS
LLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHT
CLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKML
LMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELL
GATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKE
VNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADS
GNFKRCINLWKYALDMQQSN
Ligand information
>7jya Chain D (length=10) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RRRRWRERQR
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7jya Molecular basis for ubiquitin ligase CRL2 FEM1C -mediated recognition of C-degron.
Resolution2.46 Å
Binding residue
(original residue number in PDB)		S117 R121 F125 D126 H148 H150 Y158 S179 K181 N183 D188 E191 D211 Y213 V223 T224 D336 Y339
Binding residue
(residue number reindexed from 1)		S116 R120 F124 D125 H147 H149 Y157 S178 K180 N182 D187 E190 D210 Y212 V222 T223 D335 Y338
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7jya, PDBe:7jya, PDBj:7jya
PDBsum7jya
PubMed33398170
UniProtQ96JP0|FEM1C_HUMAN Protein fem-1 homolog C (Gene Name=FEM1C)

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