Structure of PDB 7jx7 Chain A Binding Site BS01
Receptor Information
>7jx7 Chain A (length=111) Species:
9606
(Homo sapiens) [
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GSSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPM
DLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQD
VFEFRYAKMPD
Ligand information
>7jx7 Chain B (length=6) Species:
32630
(synthetic construct) [
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GGKAGK
Receptor-Ligand Complex Structure
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PDB
7jx7
The bromodomains of BET family proteins can recognize diacetylated histone H2A.Z.
Resolution
1.75 Å
Binding residue
(original residue number in PDB)
W370 Y428 N429 P430 H433 V435
Binding residue
(residue number reindexed from 1)
W26 Y84 N85 P86 H89 V91
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7jx7
,
PDBe:7jx7
,
PDBj:7jx7
PDBsum
7jx7
PubMed
33247496
UniProt
P25440
|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)
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