Structure of PDB 7jwj Chain A Binding Site BS01

Receptor Information
>7jwj Chain A (length=266) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPW
MEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGC
DLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSG
AAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVTL
RCWALGFYPADITLTWQLNGEDMELVETRPAGDGTFQKWASVVVPLQNYT
CRVYHEGLPEPLTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7jwj Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
Resolution3.251 Å
Binding residue
(original residue number in PDB)		Y7 E63 K66 Q70 W73 S77 N80 Q97 F116 Y123 T143 K146 W147 S150 H155 Y156 Y159 W167
Binding residue
(residue number reindexed from 1)		Y6 E62 K65 Q69 W72 S76 N79 Q96 F115 Y122 T142 K145 W146 S149 H154 Y155 Y158 W166
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:7jwj, PDBe:7jwj, PDBj:7jwj
PDBsum7jwj
PubMed34083463
UniProtP01899|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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