Structure of PDB 7jof Chain A Binding Site BS01

Receptor Information
>7jof Chain A (length=122) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGMLRVFILYAENVHTPDTDISDAYCSAVFAGVKKRTKVIKNSVNPVWNE
GFEWDLKGISELHVVVKDHETMGRNRFLGEAKVPLREVLATPSLSASFNA
PLLDTKKQPTGASLVLQVSYTP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7jof Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7jof Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D18 D21 D71 H72 E73
Binding residue
(residue number reindexed from 1)		D20 D23 D68 H69 E70
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7jof, PDBe:7jof, PDBj:7jof
PDBsum7jof
PubMed33449082
UniProtO75923|DYSF_HUMAN Dysferlin (Gene Name=DYSF)

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