Structure of PDB 7jl7 Chain A Binding Site BS01

Receptor Information
>7jl7 Chain A (length=141) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FRYSLNYPNIGHCIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYI
VKVYNDQTVAQIMQVLTTVAHDDHSRCASLVCVLLSHGDEGVFFGTDTSV
DLKSLTSLFRGDRCPSLVGKPKLFFIQACRGTELDPGVETD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7jl7 Remodeling hydrogen bond interactions results in relaxed specificity of Caspase-3.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		R67 H124 Q164 C166
Binding residue
(residue number reindexed from 1)		R30 H87 Q127 C129
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7jl7, PDBe:7jl7, PDBj:7jl7
PDBsum7jl7
PubMed33448281
UniProtA0A2R8QUC0

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