Structure of PDB 7jk4 Chain A Binding Site BS01

Receptor Information

>7jk4 Chain A (length=401) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TPSQKMKKIRAGELSPSMQQRTDLPAKDSSKSELQLAREQLHVSVVPKSL
PCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRM
AKQNELPAFEYLEINGMRLTEPRQAYVQIYKQLTGKTVSWEQAHALLEKR
FTTPAPRRVTTVLLVDELDILCNRRQDVVYNLLDWPTKSAAKLVVVTIAN
TMDLPERLLMGKVTSRLGLTRLTFQPYSHKQLQEIVTARLGGSETFKGEA
VQLVARKVAAVSGDARRALDICRRATEIADTAAVKCVTMLHVQQALAEMI
ASAKVQAIRNCSRMEQIFLQAIAAEVTRTGVEETTFMGVYQQVETIAAFM
GVTFPPPGRALRLCSKLGAERLIISEHSRNDLFQKILLNVSADDIHYALR
V

Ligand information

>7jk4 Chain I (length=34) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aaaagcaagcataaaagatctaaacataaaatct

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7jk4 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution	3.4 Å
Binding residue (original residue number in PDB)	K525 N691 R692
Binding residue (residue number reindexed from 1)	K7 N173 R174

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005524	ATP binding
GO:0016887	ATP hydrolysis activity

View graph for
Molecular Function

External links

PDB	RCSB:7jk4, PDBe:7jk4, PDBj:7jk4
PDBsum	7jk4
PubMed	32848132
UniProt	O16810\|ORC1_DROME Origin recognition complex subunit 1 (Gene Name=Orc1)

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