Structure of PDB 7jhd Chain A Binding Site BS01
Receptor Information
>7jhd Chain A (length=224) Species:
9606
(Homo sapiens) [
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ALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTDH
IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEH
LYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>7jhd Chain C (length=8) Species:
9606
(Homo sapiens) [
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KILHRLLQ
Receptor-Ligand Complex Structure
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PDB
7jhd
Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer.
Resolution
2.402 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 D538 E542
Binding residue
(residue number reindexed from 1)
I46 L60 V64 D214 E218
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7jhd
,
PDBe:7jhd
,
PDBj:7jhd
PDBsum
7jhd
PubMed
33177154
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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