Structure of PDB 7ftn Chain A Binding Site BS01
Receptor Information
>7ftn Chain A (length=353) Species:
9606
(Homo sapiens) [
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GASKLRAVLEKLKLSRDDISTAAGMVNGVVDHLLRRLKCDSAFRGVGLLN
TGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKPKENPL
SQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLI
SEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPK
HAKQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLL
EQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNC
VTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFP
VFD
Ligand information
>7ftn Chain B (length=16) [
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aaattgccgaagacga
Receptor-Ligand Complex Structure
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PDB
7ftn
Crystal Structure of a human cyclic GMP-AMP synthase complex
Resolution
2.001 Å
Binding residue
(original residue number in PDB)
L174 R176 K198 H217 K407
Binding residue
(residue number reindexed from 1)
L14 R16 K38 H57 K240
Enzymatic activity
Enzyme Commision number
2.7.7.86
: cyclic GMP-AMP synthase.
External links
PDB
RCSB:7ftn
,
PDBe:7ftn
,
PDBj:7ftn
PDBsum
7ftn
PubMed
UniProt
Q8N884
|CGAS_HUMAN Cyclic GMP-AMP synthase (Gene Name=CGAS)
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