Structure of PDB 7fhk Chain A Binding Site BS01

Receptor Information
>7fhk Chain A (length=663) Species: 3702,6100 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVRRSEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIF
TRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTN
AESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDV
LVDFLYLFLPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALW
MLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIP
AYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMK
RRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFD
ELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQL
RAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGW
IYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPDENTF
FSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIF
CVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTL
FNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLE
AFFTELDLEEEEK
Ligand information
>7fhk Chain B (length=12) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7fhk Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		L375 R398
Binding residue
(residue number reindexed from 1)		L352 R375
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005216 monoatomic ion channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0042802 identical protein binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006811 monoatomic ion transport
GO:0006816 calcium ion transport
GO:0008218 bioluminescence
GO:0009845 seed germination
GO:0010119 regulation of stomatal movement
GO:0019722 calcium-mediated signaling
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0080141 regulation of jasmonic acid biosynthetic process
Cellular Component
GO:0000325 plant-type vacuole
GO:0005575 cellular_component
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0034702 monoatomic ion channel complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7fhk, PDBe:7fhk, PDBj:7fhk
PDBsum7fhk
PubMed34845029
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
Q94KI8|TPC1_ARATH Two pore calcium channel protein 1 (Gene Name=TPC1)

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