Structure of PDB 7fbl Chain A Binding Site BS01

Receptor Information
>7fbl Chain A (length=130) Species: 1935377 (Corticium sp. (in: basidiomycete fungi)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ACTTGPQTISFPAGLIVSLNASVQSSRNESVEVKDSNGNTVSRGSGSSSS
GGTFTVINMEPPTFISDGNDYTVELSPQATPGILQTESSRVDNGRLIWQN
YAFGANDGGCIVGDRDFNDVFVLITGLVRG
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain7fbl Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7fbl A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.
Resolution1.419 Å
Binding residue
(original residue number in PDB)		S26 S27 D108 D115 D117 D120
Binding residue
(residue number reindexed from 1)		S25 S26 D107 D114 D116 D119
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7fbl, PDBe:7fbl, PDBj:7fbl
PDBsum7fbl
PubMed36433967
UniProtC0HM62|THRCO_CORXX Thrombocorticin

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