Structure of PDB 7exq Chain A Binding Site BS01

Receptor Information
>7exq Chain A (length=718) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PAVRISDGNLIIKNRTILTGVPDNVITTSASEAGPVEGVFVGAVFNKEES
KHIVPIGTLRNSRFMSCFRFKLWWMAQRMGEMGRDIPYETQFLLVESNKV
YTVFLPLIEGSFRSCLQGNVNDEVELCLESGDVDTKRSSFTHSLYIHAGT
DPFQTITDAIRTVKLHLNSFRQRHEKKLPGIVDYFGWCTWDAFYQEVTQE
GVEAGLKSLAAGGTPPKFVIIDDGWQSVERDASPIFRLTGIKENEKFKKK
DDPNVGIKNIVKIAKEKHGLRYVYVWHAITGYWGGVRPGEEYGSVMKYPN
MSKGVVENDPTWKTDVMTLQGLGLVSPKKVYKFYNELHSYLADAGVDGVK
VAVQCVLETLGGGLGGRVELTRQFHQALDSSVAKNFPDNGCIACMSHNTD
ALYCSKQAAVIRASDDFYPRDPVSHTIHIASVAYNSVFLGEFMQPDWDMF
HSVHPAAEYHASARAISGGPLYVSDSPGKHNFELLRKLVLPDGSILRARL
PGRPTRDCLFADPARDGVSLLKIWNMNKYTGVLGVYNCQGAAWSSTERKN
IFHQTKTDSLTGSIRGRDVHSISEASTDPTTWNGDCAVYSQSRGELIVMP
YNVSLPVSLKIREHEIFTVSPISHLVDGVSFAPIGLVNMYNSGGAIEGLR
YEAEKMKVVMEVKGCGKFGSYSSVKPKRCVVESNEIAFEYDSSSGLVTFE
LDKMPIENKRFHLIQVEL
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain7exq Chain C Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7exq Structural insight into the hydrolase and synthase activities of an alkaline alpha-galactosidase from Arabidopsis from complexes with substrate/product.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		K75 T342 D346
Binding residue
(residue number reindexed from 1)		K71 T311 D315
Annotation score2
Enzymatic activity
Enzyme Commision number 2.4.1.82: galactinol--sucrose galactosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0047274 galactinol-sucrose galactosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7exq, PDBe:7exq, PDBj:7exq
PDBsum7exq
PubMed36762861
UniProtQ8RX87|RFS6_ARATH Probable galactinol--sucrose galactosyltransferase 6 (Gene Name=RFS6)

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