Structure of PDB 7ev6 Chain A Binding Site BS01

Receptor Information
>7ev6 Chain A (length=594) Species: 172827 (Meiothermus taiwanensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLSYEALEWRTPIENSTEPVSLPPPPPFFGQERAREALELAIRGGFHAY
LVGPPSLGKHEALLAYLSTQSVETPPDLLYVPLSERKVAVLTLPSGQEIH
LAEAVEGLFQRFPQARAYLEALRARYAETGEPLAQWRPNLLTSSSSGTPP
PIVYEPYATAPRLFGRLDYLVWSTNVSLIRPGAVHRAQGGYLILDALSLK
REGTWEAFKRALRNGQVEPVTEPQAPAGLEVEPFPIQMQVILVGTPEAFE
GLEEDPAFSELFRIRAEFSPTLPASPENCTALGGWLLAQGFQLTQGGLTR
LYDEARRMAEQRDRMDARLVEIRALAEEAAVLGGGLLTAESVEQAIAARE
HRSFLSEEEFLRAVQEGVIRLRTTGRAVGEVNSLVVVEAAPYWGRPARLT
ARAAPGRDHLISIDREAGLGGQIFHKAVLTLAGYLRSRYIEHGSLPVTIS
LAFEQNYVSIEGASAGLAELVAALSAIGNLPLRQDLAVTGAVDQTGKVLA
VGAINAKVEGFFRVCKALGLSGTQGVILPEANLANLTLRAEVLEAVRAGQ
FHIYAVETAEQALEILAGARMEGFRGLQEKIRAGLEAFARLEEG
Ligand information
Receptor-Ligand Complex Structure
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PDB7ev6 Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		V503 V504 E506 Y575 S577 I578 E579 G580 S582 A583 G620 K625
Binding residue
(residue number reindexed from 1)		V385 V386 E388 Y457 S459 I460 E461 G462 S464 A465 G502 K507
Enzymatic activity
Enzyme Commision number 3.4.21.53: endopeptidase La.
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005524 ATP binding
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0030163 protein catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7ev6, PDBe:7ev6, PDBj:7ev6
PDBsum7ev6
PubMed34757797
UniProtC9DRU9

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