Structure of PDB 7ev4 Chain A Binding Site BS01

Receptor Information
>7ev4 Chain A (length=592) Species: 172827 (Meiothermus taiwanensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLSYEALEWRTPIENSTEPVSLPPPPPFFGQERAREALELAIRGGFHAY
LVGPPSLGKHEALLAYLSTQSVETPPDLLYVPLSERKVAVLTLPSGQEIH
LAEAVEGLFQRFPQARAYLEALRARYAETGEPQWRPNLLTSSSSGTPPPI
VYEPYATAPRLFGRLDYLVWSTNVSLIRPGAVHRAQGGYLILDALSLKRE
GTWEAFKRALRNGQVEPVTEPQAPAGLEVEPFPIQMQVILVGTPEAFEGL
EEDPAFSELFRIRAEFSPTLPASPENCTALGGWLLAQGFQLTQGGLTRLY
DEARRMAEQRDRMDARLVEIRALAEEAAVLGGGLLTAESVEQAIAAREHR
SFLSEEEFLRAVQEGVIRLRTTGRAVGEVNSLVVVEAAPYWGRPARLTAR
AAPGRDHLISIDREAGLGGQIFHKAVLTLAGYLRSRYIEHGSLPVTISLA
FEQNYVSIEGDAAGLAELVAALSAIGNLPLRQDLAVTGAVDQTGKVLAVG
AINAKVEGFFRVCKALGLSGTQGVILPEANLANLTLRAEVLEAVRAGQFH
IYAVETAEQALEILAGARMEGFRGLQEKIRAGLEAFARLEEG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7ev4 Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Resolution2.12 Å
Binding residue
(original residue number in PDB)		V503 V504 E506 V576 S577 I578 E579 G580 A582 G620 K625
Binding residue
(residue number reindexed from 1)		V383 V384 E386 V456 S457 I458 E459 G460 A462 G500 K505
Enzymatic activity
Enzyme Commision number 3.4.21.53: endopeptidase La.
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005524 ATP binding
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0030163 protein catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7ev4, PDBe:7ev4, PDBj:7ev4
PDBsum7ev4
PubMed34757797
UniProtC9DRU9

[Back to BioLiP]